An agent from ICE shows up at Grey Sloan in search of an employee who may be working in the U.S. under DACA. Alex’s patient Kimmie wants to leave the hospital to enjoy her final days, but Alex feels differently. Meanwhile, Arizona treats Matthew Taylor’s baby and April wants to do whatever she can to help.

Amelia, Koracick and DeLuca perform a risky, groundbreaking procedure using ultrasound waves to remove a young patient’s brain tumor. Meanwhile, Meredith and Jo work with different polymers to try to salvage their project submission; and Richard’s AA sponsor is admitted to Grey Sloan with a DNR.

April's crisis of faith is challenged by a patient she treats who is a rabbi, and Meredith treats a patient who is a transplant surgeon from another hospital.

Maggie and Jackson are enjoying spending time together, but he must turn his concentration toward the groundbreaking vaginoplasty surgery he has scheduled with Catherine and Richard. Meanwhile, Meredith and Jo hit a roadblock with their contest submission, so Jo helps Bailey with an incoming trauma patient who used to be an astronaut

Meredith tries to learn more about Marie Cerone's history with her mother. Meanwhile, Jo is applying for fellowships around the country and it throws Alex for a loop; and Tom Koracick helps April acknowledge her crisis of faith.

Maggie's relationship with Clive starts to progress; she invites him over for a game night to meet Meredith and Amelia; Meredith and Jo meet with the owner of the patent to the polymer they need for their project, who is a friend of the family.

Seattle firefighters Ben Warren and Andy Herrera head to Grey Sloan after rescuing two boys who were injured in a house fire; the doctors work on their projects for the surgical innovation contest; Amelia brings Tom Koracick in to consult.

April is in charge of the new Grey Sloan Surgical Innovation Contest, and the doctors are eager to start their projects. Meanwhile, Catherine’s old friend has a shocking idea for Catherine and Jackson; and Meredith treats a returning patient who inspires her project.

The stress of managing the hospital and coming to terms with Ben’s decision to become a Seattle firefighter pushes Bailey to her limits.

Jackson decides he needs some time off and invites the guys to join him on a day out at sea. Meanwhile, Arizona, April and Maggie treat a woman who’s hiding a deadly secret.