When flight attendant Cassie Bowden meets passenger Alex Sokolov, she decides to spend an extravagant, very drunk night with him. But when she wakes up the next morning beside a dead body – and with no memory of what happened – Cassie fights to keep her wits about her long enough to make it back to New York, where more trouble looms.

CNO Tom Chandler is sent to Asia to investigate a possible mutation of the Red Flu. Captain Slattery and his crew deliver cure to Southeast Asia but there may be an unexpected threat in the region.

Erlich has new competition. The Pied Piper staff has a hard time giving less than their all. Monica stands her ground. Gavin reaches a decision about Nucleus.

Since she was young, Clare has had an imaginary friend – a kind and funny man, sometimes old, sometimes young, who appears in the woods behind her house and tells her tales of the future.

With their mission now fully dedicated to spreading the cure, Nathan James puts a call out to civilians to meet at pre-selected ports across the country.

Nathan James finds itself trapped between the submarine and civilian blockades.

After a message is broadcast implicating the Navy in a devastating disaster, Chandler looks to infiltrate the network and regain the trust of the American people.