J. Jonah Jameson hires Dr. Farley Stillwell who is a raining genius in genetic engineering, to make a new super hero that can match and defeat Spider-Man. With a willing participant, Mac Gargain, they engineer the DNA of a scorpion and him together to form a new hero, The Scorpion. However, when Mac thinks they have turned him into a freak, hero turns to monster and he goes on a rampage. Spider-Man is then forced to step in to stop creation from killing creator.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/6 (https://www.frederickcalica.com/?p=3371253)
The Master of Illusion, Mysterio has fooled the city and J. Jonah Jameson into thinking Spidey has turned to crime. However Spidey manages to find Mysterio only to be brought to a trap of special effects.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/5 (https://www.frederickcalica.com/?p=3371160)
Dr. Otto Octavius becomes the mad Dr. Octopus when his robotic arms become fused to him in a laboratory accident. He then seeks revenge for the humiliation the Hardy Foundation has caused him. He kidnaps Felicia and holds her ransom. So it is once again, Spidey to the rescue.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/4 (https://www.frederickcalica.com/?p=3370569)
With Spencer Smythe dead, his son Alistair turns to the Kingpin to help seek his revenge on Spider-Man and others he deems responsible for his father's death. He captures, Eddie Brock, J. Jonah Jameson, Norman Osborn, and Flash Thompson. He then turns his sights on Spidey and sends three slayers after him. Spidey only manages to hold his ground while fighting them individually. However, he is not so lucky when they combine into a super slayer and carry him off to Smythe.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/3 (https://www.frederickcalica.com/?p=3369435)
Norman Osborn hires Spencer Smythe to design a machine capable of destroying Spider-Man - the Black Widow Spider Slayer. But when Flash Thompson puts on a Spider-Man costume as a party gag, the deadly machine spots him, and he's carried off in Peter's place.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/2 (https://www.frederickcalica.com/?p=3369017)
Peter Parker and his college science professor Dr. Curt Conners explore neogenics as a method of limb regeneration. But while experimenting on himself, Connors accidentally becomes the Lizard, a half-man, half-reptile monstrosity that terrorizes Manhattan and subsequently kidnaps his own wife. Spider-Man's task is doubly difficult because he doesn't want to hurt the good friend he knows is trapped inside...but he must stop the inhuman beast who is out of control.
https://trakt.tv/shows/spider-man-the-animated-series/seasons/1/episodes/1 (https://www.frederickcalica.com/?p=3368975)
